Study uses mass spectrometry to identify and analyze bacteria.
Aliyah Barrett ’09 presented a poster, “Coupling MALDI-TOF MS Whole-cell Analysis of Escherichia Coli with Microfluidic Culturing” at Randolph College’s Symposium for Artists & Scholars on April 17, 2009.
Aliyah conducted the research project with her faculty mentor, William Bare, associate professor of chemistry, while an undergraduate student at Randolph College.
An abstract of poster follows...
Matrix-assisted laser desorption/ionization (MALDI) mass spectrometry can positively determine the species and even strain of bacteria and other microorganisms. This technique can generate distinct spectra produced from whole cells, allowing very rapid identification. However, variability in spectra is a barrier to identification. Coupling MALDI mass spectroscopy with microfluidic culturing could help produce consistent spectra. The precise control over environment, batch testing capability, and all-in-one functionality permitted by microfluidic devices promises to improve the speed and accuracy of this technique.
The Student Symposium of Artists and Scholars provides Randolph College students from all classes and disciplines the opportunity to present the results of their research, scholarship, and creative work to the entire College community and beyond.
The two-day symposium, modeled after a typical academic conference, features oral presentations of student research, readings of creative work, musical performances, and exhibitions of student artwork. The symposium also includes a poster session, reception and a keynote address from a noteworthy academic speaker.
Learn more at www.randolphcollege.edu/sas